The Nightfall is the Splicer Priest and Ogre
Ironclad (more enemies have shields [knights will have arc shields, shanks will have solar shields])
Brawler (Melee damage is greatly boosted [this includes shoulder charge and throwing knife, maybe smoke too])
Arc Burn (all sources of arc damage do increased damage [Use Zhalo Supercell along with an arc subclass and please, for the love of God, be careful around shanks])
Exposure (Guardians have immensely powerful shields, but your health will recharge slowly [There are no weapon perks to negate this, Red Death will make your shield regen at the slower speed. However, you will always fill up your red health bar at normal speed before the regen slows down.])
MAIN TIPS: Be careful around those shanks in the boss room. I would personally run an Arc sidearm for close encounters. Good luck!